These images of
the impressions taken from one of the people before and after 28
days of treatment show perfectly that had a markedly beneficial effect on the network of
small depressions on the surface of the skin. Quantitative analysis
of the results show that, 28
days of topical of the formulation markedly reduced the depth of medium-deep wrinkles and clearly
diminished the total area of wrinkled skin (-3mm2)
Diagram 1: Number of
people (on %) presenting a real reduction of wrinkle results
obtained
Regular
application to the skin markedly improves its
moisture content.
The skin is more
flexible, less ''tight-feeling'' and more comfortable.
Results:
After 28 days of
treatment,
increased skin moisture
content by 18% more than the placebo.
Impressions of the
people
immediately after application
of the product
80% of the people said that their skin felt hydrated
after application of the product
60% of the people
said that application of the product made their skin feel stimulated
and rejuvenated
Impressions of the people
after 28 days
of treatment
66.5% of the
people observed a definite improvement in the condition of their
skin
73.5% of the
people observed that their skin had definitely become softer
60% of the
people found that their skin was definitely more hydrated
60% of the
people reported that the product made their skin smoother
By remodelling
and protecting
the major structural elements of the dermis, it not only reduces the depth of the wrinkles
but also helps moisturize
the skin.
Because it both
protects elastin
molecules and reduces
free radical mediated damage,
it represents a powerful weapon in the fight mitigate
the effects of the ageing
process of the skin.
One month of
treatment reinforces skin structure. the protected
and strengthened
skin can then discover its former resistance and tone (demonstrated in vitro tests ).
When its structure
is improved, the skin's moisture
content improves and wrinkles
and crow's feet are smoothened away (demonstrated in clinical tests
on real people).
Exposure to UV Radiation, Stress,
pollution, alcohol and tabacco smoke
can increase free radicals on the skin with serious consequences for
the body's cells, and can cause cell death, damage important
components of connective tissue (eg. elastin and collagen) which
will, in the long term, accelarate ageing of the skin.
A potent scavenger of free radicals, so effeciently
protects cells
and their components from damage. Such protection is essential to
keep the skin in good condition.
EFFECT 2: WHITENING AND
LIGHTENING OF THE SKIN
Partnec 8's whitening ingredient's development is the result of a
research program in which about a hundred plants were selected for
their tyrosinase-inhibiting capacity.
Of
the hundred plants tested, 15 were selected for their in vitro
tyrosinase inhibiting activity and were subsequently tested on cell
cultures. In the cell cultures, seven plants manifested even greater
tyrosinase-inhibiting activity.
The
plants were combined in a proprietary and synergistic ratio
maximizing its activity and producing an even more effective
compound. In lab tests and also in the tests on real people it's
effect has been proved for whitening.
Organically grown 7 Swiss alpine plants are inside Partnec 8
Malva
Sylvestris (Mallow) Extract, Mentha Piperita (Peppermint) Leaf
Extract, Primula Veris Extract, Alchemilla Vulgaris Extract,
Veronica Officinalis Extract, Melissa Officinalis Leaf Extract,
Achillea Millefolium Extract
Another ingredient of Partnec 8 DAB is an instant and
gradual skin brightener.
Visible lightening after one month
Clinical tests on
real people:
Instant effect: Even,
luminous, mat complexion
Naturally looking
brightness on the skin immediately after applying.
Gradual effect:
Physiological skin lightening
Clinical tests
on 27 women, age 34±2. Twice daily application for 56 days
RESULTS:
-
Significant and gradual
decrease of the melanin in the skin.
-
Skin luminosity is
improved.
-
Skin is less yellow.
-
In just 1 month, more
than 80% women tested had an improvement.
-
All the women tested are
satisfied with the product efficacy, they noticed a lightening
effect on their skin, immediately and after 2 months.
CLINICAL TEST PICTURE
EFFECT 3: DEEP
MOISTURIZING
<Common hyaluronic acid>
The skin is covered by
hyaluronic acid as if it is membrane.
Loss of skin moisture is
prevented.
Skin
moisture is kept.
Common hyaluronic acid is
easily washed away because it doesn’t penetrate into the skin
Partnec's
ingredient is quite a new hyaluronic acid with very low molecular weight (av.7,000
da).
Since it covers the skin surface and also penetrates
into horny layer,
it keeps the skin moisture both inner and outer side of the skin.
Penetrates into the
horny layer of the skin
It remains in horny layer of
the skin is not washed away, thus unlike common hyaluronic acid,
it retains the skin moisture even
after washing.
Keeps
skin moisturized during 3 days after application.
Applied the lotion sample to
11 females’ one side of their faces, followed by washing and normal
care, then compared the condition with non-applied side.
Smooth silky touch
●More than half of the
subjects felt improvement in smooth silky touch.
●On the 20th day of use, more subjects felt the touch.
Softness
●More than 70% of the subjects felt softness.
●On the 20th day of use
,more subjects felt the softness.
EFFECT 4:
TIGHTENING, FIRMING
DPHP - An amino acid through a plant-derived
biological vehicle.
TRIPLE FIRMING ACTION
Partnec 8's ingredient has triple
action against the cause of cell funtion loss by protecting and firming the
skin and so restores the skin's former firmness:
Promotes interactions between
fibroblasts and the dermal matrix therefore stimulating remodelling and
contraction of collegen fibers: the result is that skin tissue is consolidated
and tone is restored.
By inhibiting the over production of
eleaste enzymes, it protects eleastic fibers from enzyme-mediated breakdown,
therefore preserving the elasticity of the skin and prevents later damages.
By reducing the level of free
radicals, it protects those cellular elements of the skin which are essential
for its health and well-being.
Evaluation of the ability of
the fibroblasts to contract collagen fibres by measuring the
diameter of the collagen lattice on day 0, day 3, day 4, day 6, day
7, day 8, day 9, day 10
Significant potentiation of the fibroblasts ability to contract
collagen fibres.
Control
- after 7 days
Partnec
8's ingredient after 7 days
Compared with the Control culture, it stimulates contraction of
collagen fibres (the diameter of the lattice is reduced)
Anti-Elastase activity for preserving skin elasticity:
Compared to Vitamin C
EFFECT 5:
COVERING IMPERFECTIONS
Instant effect: Even,
luminous, mat complexion
After
10 minutes:
Pores
Creates a soft-focus
effect on all the imperfections of the skin: blemishes, lines,
skin grain, pores.
Very significant
improvement of the complexion evenness: 10.3%.
Hyperpigmented areas are
less visible.
Skin luminosity is
improved.
Skin is less yellow and
less red for most of the people tested.
EFFECT 6:
SMOOTHING, CALMING
After 28
days of treatment, the skin is rejuvenated, smoother and more fully
hydrated.
20 people tested, 19-35
years female, application over a period of 25 days, twice a day for
the soothing activity of the Partnec 8's ingredient:
CLINICAL STUDY 2
ON 30 VOLUNTEERS ON
SENSITIVE SKIN SYMPTOMS OVER 2 DAYS
·
Application site: nasolabial fold
·
Samples: o/w emulsion with 31.6 ppm capsaicin +/- 0.4 % active
·
Evaluation of the stinging effect 3 min. after application
· The
capsaicin-induced stinging and burning effect is significantly being
reduced below the sensory threshold level
·
Immediate comfort and deep relief
Partnec
8's ingredient:
> New
active ingredient for Sensitive Skin
> Represents the next
generation of neuro-sensorial actives for sensitive skin with fast
skin relief
> Works at the cell
communication level directly connecting with specific neuro-receptor
: TRPV1 thermo-receptor
> Acts as a Sensi-Regulator
reducing the calcium flux in the cellular membrane bringing back to
a normal state
> Helps to increase the
skin’s tolerance threshold by its regulating action
> Reduces
significantly burning and stinging
> Shows
an immediate effect on heating symptoms
> Is an
anti-nerve hyper-activation
> Calms
over reaction of the skin
> Reduces sensitive symptoms
EFFECT
7: REPAIRING AND PROTECTING
20 people tested, 18-33 years,
application over a period of 25 days, twice a day for the repairing function
of Partnec 8's ingredient.
The main pharmacological effect of
allantoin is the powerful stimulation of cell proliferation and the
enhancement of the rebuilding of intact granulation tissue. In pharmacological
applications, allantoin is used e.g. in the treatment of ulcers, slow-healing
wounds and burns.
In cosmetics, allantoin used as an
adjunct in numerous preperations as it enhances soothing, cleansing an healing
action.
Free-radical scavenging activity:
Free radicals are highly reactiVe
chemical species produced in body both in normal conditions and in
pathological conditions. Their rate of production can be increased due to
outside factors, such as exposure to certain chemical substances, physical
injury, UV (sun) radiation, stress, pollution, alcohol and tabacco smoke. Free
radicals have very serious consequences for the body's cells and even can
cause to cell death.
Free radicals can damage important
components of connective tissue like elastin and collagen and it will
accelerate ageing of the skin in the long term.
Our body has its own mechanisms to
detoxify free radicals but these can become overloaded and need outside help
like a skin cream which has an active material capable of scavenging free
radicals.
The activity of Partnec 8's ingredient
was compared with that of Vitamin C. which is a well-known powerful scavenger
of free radicals.
Because of its potent anti-free
radical activity, it effeciently protects cells and their components from
damage. Such protection is esseential if the skin to be kept in good
condition.
EFFECT 8:
DELAY NEW WRINKLES
The
anti-wrinkle efficacy
of the Partnec 8's main ingredient is confirmed and acts more
rapidly than retinol (and
without irritation phenomena).
Skin thickness increases by
6.5% in 2 months and 8.6% in 4 months.
Evaluation by the
Dermatologist confirms the anti-wrinkle effect, even on the forehead
and the perinasal area.
With the Partnec 8's
ingredient's long lasting moisturizing and firming action, it resculpts the
face's skin, corrects imperfections (smoothes over the marks of time) and
delays the appearance of wrinkles by protecting the fibres of the dermis.
IN VIVO (CLINICAL
SCIENTIFIC STUDY WITH REAL HUMAN BEINGS)
STUDY IN COLLOBORATION WITH PROFESSOR REVUZ FROM MONDOR HOSPITAL
Profilometry and
image analysis - 2 and 4 month study versus placebo
Two groups of 30
people/ Twice-daily application on the face and decollete for 4
months
ELASTIN
BEFORE
AFTER 4 MONTHS
Results:
Notable Increase of density and
thickness of fibres.
*
Clinical tests belong to the main
active ingredients of Partnec 8 Extra
and the clinical tests are organized by the
manufacturers of the different ingredients in France, Switzerland and USA.